Trend of putting illicit drugs in vapes growing, Oklahoma officials say Drug laced vapes pose a serious and growing public health threat. Attractive flavours and packaging can hide dangerous substances such as ketamine, fentanyl, heroin, methamphetamine, THC and synthetic opioids. Even small amounts can Will Vaping Lead Teens to Smoking Cigarettes? Johns Hopkins Medicine E Cigarettes, Vapes, and other Electronic Nicotine Delivery Systems (ENDS) FDA