Everyone says NAC can make glutathione. Wrong. Evidence against this is staring right at you. As you can see here, my wife's GCLC gene is genetically slower. Thus, she cannot convert Cysteine The Mechanism and Inflammatory Markers Involved in the Potential Use of N acetylcysteine in Chronic Pain Management Protonation Equilibria of N Acetylcysteine ACS Omega Electrochemical evidences in oxidation of acetaminophen in the presence of glutathione and N acetylcysteine Chemical Communications (RSC Publishing)