Glutathione deficiency can lead to a variety of signs and symptoms that affect your overall health. Here are some common signs to look out for: 1. **Increased Dark Spots** Glutathione Essential Fx Acyl Glutathione Rejuvenating Moisturizer Perricone MD Glutathione and Inflammation Glutathione Reporter University Did you know Glutathione is your body's master antioxidant? It protects your cells from damage, boosts energy levels, and supports your immune system, all while helping to detoxify your body.