This #GUTRecentAdvancesInBasicScience review synthesises emerging evidence linking the microbiome to cardiovascular disease, highlighting shared inflammatory and metabolic pathways. Fusco et al. present Gut microbiota and atherosclerosis access it Intestinal microbiota metabolism of l carnitine, a nutrient in red meat, promotes atherosclerosis Nature Medicine The Gut Arterial Stiffness Axis: Is TMAO a Novel Target to Prevent Age Related Aortic Stiffening? Hypertension Characterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery Microbiome Springer Nature Link