Tylenol depletes something called glutathione. Glutathione is a master antioxidant and your first line of protection against environmental toxins. It detoxifies and protects your cells. It protects your immune system and Acetaminophen's Role in Autism and ADHD: A Mitochondrial Perspective Oxidative stress mediates end organ damage in a novel model of acetaminophen toxicity in Drosophila Scientific Reports As a naturopathic doctor and a mom, Tylenol is a hard no in my house and I want to explain why. , , Acetaminophen (Tylenol) is processed through the liver, and in that process it can lower