Metabolism of Acetaminophen: Understanding the Process AI Art Generator Easy Peasy.AI The oral administration of Lacticaseibacillus casei Shirota alleviates acetaminophen induced liver injury through accelerated acetaminophen metabolism via the liver gut axis in mice mSphere Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Protective effect of apigenin on mouse acute liver injury induced by acetaminophen is associated with increment of hepatic glutathione reductase activity Food & Function (RSC Publishing)