Cagrilintide and Retatrutide for Men: Uses, Evidence, and UK Access Bolt Pharmacy Once weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double blind, placebo controlled and active controlled, dose finding phase 2 trial ScienceDirect Cagrilintide (AM833) Long acting amylin analog. Beta cells make TWO hormones: insulin and amylin. Amylin slows stomach emptying and reduces appetite. Cagrilintide is a long acting synthetic amylin designed for once weekly dosing Umbrella Labs Cagrilintide Peptide Research Use Only Program Expands Laboratory Access For High Rigor Amylin Receptor, Calcitonin Receptor, And Neuroendocrine Signaling Bench Science