Frontiers The effect of L carnitine supplementation on lipid profile in adults: an umbrella meta analysis on interventional meta analyses Carnitine metabolic disorders and novel clinical approaches: Mechanistic insights from deficiency management to liver and kidney disease treatment ScienceDirect Carnitine is an essential cofactor for transport of long chain fatty acids into mitochondria, where oxidation takes place. Carnitine deficiency leads to depressed mitochondrial oxidation of fatty acids, resulting in storage of fat Medium chain fatty acid oxidation is independent of l carnitine in liver and kidney but not in heart and skeletal muscle American Journal of Physiology Gastrointestinal and Liver Physiology American Physiological Society