Labial Lentigo (labial melanotic macule) Cancer Therapy Advisor Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Prame Positive Vulvar Melanotic Macule With Melanocytic Hyperplasia Melanotic macules of the tongue in a newborn Journal of the American Academy of Dermatology
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