Read this paper describing a large case series of patients with mast cell activation syndrome (MCAS) and comorbidities, whose MCAS associated symptoms improved significantly on GLP1 agonists. To summarize: 47 BPC 157 is one of the most popular peptides and I would say it is a great starting point if you're new to the peptides world. It's widely explored not only in the Mast cells express IL17A, IL17F and RORC in lesional psoriatic skin, are activated before therapy and persist in high numbers in a resting state with IL 17A positivity after treatment ScienceDirect Mast CellTargeting Therapies in Mast Cell Activation Syndromes Current Allergy and Asthma Reports Springer Nature Link