Dihexa is an experimental cognitive peptide that may help the brain build stronger connections between neurons instead of just temporarily boosting neurotransmitters like many nootropics do. It works through the HGF c Met pathway, Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted The HGF c Met signaling axis. After HGF binding to the c Met receptor Download Scientific Diagram Targeted Inhibition of Hepatocyte Growth Factor (HGF) c Met Signaling Download Scientific Diagram