How Often Should I Get B12 Shots? A Guide to Your Schedule B12 Shots at Home: How, Where & How Often to Inject Yourself AZ IV Medics Main benefits of B12 injections 1) Increased energy & reduced fatigue B12 helps convert food into usable energy Deficiency often causes tiredness, weakness, and low stamina 2) Healthy red blood cells Prevents How Can Vitamin B12 Shots Help Me Feel Refreshed Dr. Nasseri