A Guide to the Best Needles for B12 Injections Precision Labs B12 vitamin Store Intramuscular vs Subcutaneous Injections for vitamin B12 supplements. Needle Size for B12 Injection: 5 Must Know Tips Does size matter? Historically, a bigger needle gauge was considered better to prevent damage to red blood cells. However, our recent guidelines recommend using smaller gauge needles (2325 G) for all
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