Wilson Disease Disease & Condition Information Willis Knighton Health Top Hospitals and Doctors in Shreveport Bossier City and the Ark La Tex Wilson Disease: Symptoms & Causes What is Wilson disease? It's a rare condition where excess copper builds up in the body, affecting the function of the liver, brain, and other organs. Early signs and symptoms Wilson's Disease (Hepatolenticular Degeneration). That brownish gold circle around the cornea is the famous Kayser Fleischer (K F) Ring. It occurs due to Copper deposition in the Descemet's membrane of the eye. Classic Triad