Glutathione peroxidase has an active site selenocysteine Glutathione for Skin: Benefits Beyond Skin Brightening Substituting Selenocysteine for Catalytic Cysteine 41 Enhances Enzymatic Activity of Plant Phospholipid Hydroperoxide Glutathion Selenoproteins: Molecular Pathways and Physiological Roles Physiological Reviews American Physiological Society
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glutathione skin brightening PDF] Dissecting the role of selenothiol- versus thiol-based catalysis using the model enzyme glutathione peroxidase 4 (GPx4)