A 48 hour fast can turn standard Paracetamol into acute liver failure. Fasting depletes Glutathione, leaving the liver defenseless against toxic NAPQI. Review the latest guidelines on BMJ Best Practice: https: bestpractice.bmj.com topics en us 1010 Pyroglutamic acidosis Deranged Physiology Good ol' paracetamol: 'But an overconsumption takes its toll' Journal of Anaesthesia Practice Acute acetaminophen paracetamol toxicity
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glutathione depletion paracetamol Paracetamol is one of the most commonly used analgesic and antipyretic drugs