Glutathione depletion by BSO induces fat remodelling in mice. (A) GSH Download Scientific Diagram 5 6) By contrast, latency I Burkitt B cells were particularly vulnerable to ferroptosis induction by blockade of either cystine import, glutathione synthesis or glutathione peroxidase 4 (GPX4). Eric also found roles for The glutathione synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma Blood Cancer Journal The glutathione cycle shapes synaptic glutamate activity bioRxiv
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bso glutathione Arabidopsis mutants impaired in glutathione biosynthesis exhibit higher sensitivity towards the glucosinolate hydrolysis product allyl-isothiocyanate