GHK Cu vs AHK Cu: Which Copper Peptide Is More Effective? Could this peptide replace Botox? , Not exactly, but it is changing the future of aesthetics., GHK Cu is a regenerative copper peptide that works at the skin level to stimulate collagen, improve Botox and GHK Cu work in completely different ways. Botox reduces wrinkles by relaxing the muscles in your face so they cannot contract as strongly. When the muscles stop moving as much, the skin GHK Cu Cooper Peptide: The Complete Skin & Repair Guide (2026)