Enhanced B Raf mediated NRF2 gene transcription and HATs mediated NRF2 protein acetylation contributes to ABCC1 mediated chemoresistance and glutathione mediated survival in acquired topoisomerase II poison resistant cancer cells ScienceDirect Multifaceted Roles of Glutathione and Glutathione Based Systems in Carcinogenesis and Anticancer Drug Resistance Elie Hatem, Nadine El Banna, Meng Er Huang, 2017 The KEAP1 NRF2 System: a Thiol Based Sensor Effector Apparatus for Maintaining Redox Homeostasis Physiological Reviews American Physiological Society NRF2 supports non small cell lung cancer growth independently of CBP p300 enhanced glutathione synthesis EMBO Reports Springer Nature Link
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glutathione nrf2 Study proposes a new strategy to intervene glutathione metabolism in the treatment of glioma