The reasons why CYSTEINE is considered the rate limiting factor in intracellular GLUTATHIONE production in our Body Low Concentration within our cells Not readily bioavailable in our DIET The Cysteine Figure 4. Intracellular GSH content in A549 cells after 1 day treatment. Glutathione measurement in A549 cells unexposed (control) and exposed to increasing concentrations (10 100 g ml) of Cd SiNPs, CdCl2, SiNPs after How Do Cells Produce Glutathione? Glutathione Reporter Glutathione mediated nanomedicines for cancer diagnosis and therapy ScienceDirect