The GHK Cu delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF 16 SKN 1 pathways Biogerontology Springer Nature Link The naturally occurring peptide GHK reverses age related fibrosis by modulating myofibroblast function He Aging Pathobiology and Therapeutics Synergy of GHKCu and hyaluronic acid on collagen IV upregulation via fibroblast and exvivo skin tests Jiang 2023 Journal of Cosmetic Dermatology Wiley Online Library GHK Cu may Prevent Oxidative Stress in Skin by Regulating Copper and Modifying Expression of Numerous Antioxidant Genes
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endogenous ghk-cu levels decline with age Intermediate Cu(II)-Thiolate Species in the Reduction of Cu(II)GHK by Glutathione: A Handy Chelate for Biological Cu(II) Reduction