COPD and Vaping: Understanding the Risks and Long Term Effects Frontiers B cell immune repertoire sequencing in tobacco cigarette smoking, vaping, and chronic obstructive pulmonary disease in the COPDGene cohort Vaping and COPD: Is it okay or can it cause more problems? A new study published in Nicotine & Tobacco Research found that those using e cigarettes alone were more than twice as likely to develop COPD than people who didn't use any tobacco products,